Press Release

[News Release] VLP Therapeutics Japan initiates Phase 1 clinical trial of T-cell inducing COVID-19 vaccine: advancing the development of a universal vaccine against multiple SARS-CoV-2 variants

2026-04-08T23:42:16-04:002026.03.31|

VLP Therapeutics Japan, Inc. (VLPT Japan), a Tokyo-based biotech company, announced on March 31 the initiation of a Phase 1 clinical trial in Japan for its COVID-19 vaccine (VLPCOV-U-01). VLPCOV-U-01 is a novel T-cell inducing mRNA vaccine designed to prevent the onset and progression of COVID‑19. Currently approved mRNA vaccines are based on humoral immunity,

[News Release] VLP Therapeutics Japan reports safety, immunogenicity, and optimal dosing of VLPCOV-02, a SARS-CoV-2 saRNA vaccine with modified 5-methylcytosine base [iScience]

2026-02-08T20:20:09-05:002026.02.06|

VLP Therapeutics Japan, Inc. (VLPT Japan) researchers and their colleagues at the National Institutes of Biomedical Innovation, Health and Nutrition (NIBN) in Japan published a paper in iScience online reporting safety, immunogenicity, and optimal dosing of VLPCOV-02, a SARS-CoV-2 saRNA vaccine with modified 5-methylcytosine base. This research was supported by AMED under Grant Number JP21nf0101627.

[News Release] VLP Therapeutics awarded US$ 2.8 million grant to develop novel malaria vaccines that improve protection, reduce costs, expand equitable access

2025-12-11T01:13:20-05:002025.12.11|

Maryland, US-based biotech company VLP Therapeutics, Inc. (VLPT) announced today that it has been awarded a two-year grant of over US$ 2.8 million (about JPY 433 million) from the Gates Foundation to develop next-gen multi-stage malaria vaccines. As an additional site for this work, a portion of the budget will also be earmarked for VLPT

[News Release] VLPT, Boston U, NIH researchers harness 5-methylcytidine to fine-tune immune responses in replicon mRNA vaccines, paving the way for safer next-gen immunization [Science Translational Medicine]

2026-02-06T05:56:31-05:002025.11.13|

VLP Therapeutics, Inc. (VLPT) researchers and their colleagues at Boston University and the National Institutes of Health (NIH) have demonstrated that incorporating a modified base known as 5-methylcytidine (5mC) into replicon-based self-amplifying RNA (saRNA) vaccines for COVID-19 can suppress innate immune responses that cause adverse reactions, while maintaining strong immunogenicity. This replicon platform technology is

[News Release] VLP Therapeutics Teams with Swedish AI Biotech Nygen Analytics on Vinnova-Funded Cancer Immunotherapy Research

2025-11-11T07:35:13-05:002025.11.11|

Swedish-US partnership to develop predictive models that could transform personalized cancer treatment selection Gaithersburg, USA and LUND, Sweden, 11 November 2025 – Nygen Analytics AB, a pioneer in AI-powered single-cell analysis technology, announced today it has been awarded a 1 million SEK (~ $105,000) grant from Vinnova, Sweden's innovation agency, to develop AI-driven predictive models

[News Release] VLP Therapeutics initiates Phase 1 clinical trial of cancer treatment with Stanford Medicine: opening the door to tumor immunotherapy with VRP technology

2025-09-19T06:52:47-04:002025.08.27|

VLP Therapeutics, Inc. (VLPT), Maryland, US-based biotech company, announced on August 27 the initiation of a Phase 1 clinical trial of VLPONC-01, a new cancer immunotherapy, in collaboration with Stanford Medicine. The trial (NCT06736379) is being conducted at Stanford Health Care with the primary objectives of assessing the safety of cancer immunotherapy and identifying

[News release] Lyophilized SARS-CoV-2 self-amplifying RNA vaccines for microneedle Array patch delivery [Journal of Controlled Release]

2025-06-16T06:20:06-04:002025.06.09|

VLP Therapeutics, Inc. (VLPT) researchers and their colleagues at Stanford University and the University of North Carolina at Chapel Hill reported their findings online ahead of print in the Journal of Controlled Release, a peer-reviewed medical journal with an impact factor of 10.5 published by Elsevier. Stanford took the lead in this collaborative work. Title:

[News Release] VLP Therapeutics wins investment from GHIT Fund for dengue vaccine clinical trial

2025-03-17T11:47:58-04:002025.03.17|

Maryland, US-based biotech company VLP Therapeutics, Inc. (VLPT) announced today that it has been awarded an investment totaling 885 million yen (about US$6 million) from the Global Health Innovative Technology (GHIT) Fund for a Phase I clinical trial of novel dengue virus-like-particle (VLP) vaccines. VLPT will share the funding (RFP-PD-2024-001) with its collaboration partners, Johns

[News Release] VLP Therapeutics makes dengue vaccine that induces antibodies, reduces replication in monkeys: Taking a step closer to next-gen dengue vaccine [Journal of Virology]

2024-05-19T09:59:15-04:002024.04.22|

VLP Therapeutics, Inc. (VLPT) researchers and their colleagues at Nagasaki University and the National Institute of Infectious Diseases in Japan have demonstrated that immunization of monkeys with a tetravalent dengue virus-like particle-based (DENVLP) vaccine induces high levels of neutralizing antibodies and reduces the severity of infection for all four dengue serotypes. The researchers also found

[News Release] VLP Therapeutics Japan reports safety and immunogenicity of VLPCOV-02, a SARS-CoV-2 self-amplifying RNA vaccine with a modified base, 5-methylcytosine [iScience]

2024-05-19T09:59:43-04:002024.01.23|

VLP Therapeutics Japan, Inc. (VLPT Japan) researchers and their colleagues at the National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), the National Hospital Organization Nagoya Medical Center, and Hokkaido University's School of Medicine in Japan published a paper in iScience online reporting safety and immunogenicity of VLPCOV-02, a SARS-CoV-2 self-amplifying RNA vaccine with a

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